I think there is some space to improve the profile handling.
These are some points from my side:
- Option to add different extruder configs (like "left extruder", "both extruders", "right extruder")
- Option to select which settings are changed by quality, filament and extruder auto settings.
For example adobe light room has a beautyfull option here. If you save a profile than it opens a list with all the settings. Than you are able to select each setting you want to save to this profile. So you are then able to select for example if the filament or the quality setting manage the printing speed.