On the CR10, you can adjust the babystep on the fly. I adjusted it while it was priming to get a proper layer. During the brim or an actual print...tried many times, no adjustment will yield layers to be laid down. I have been printing for many years and am at a loss on this one. Hence the reason why I question the setting in the profile now. I have tried many different temps for bed/hotend, striaght glass, glass and PEI...its just very odd that the prime will print proper but nothing else. Hell, i now even have marks on my PEI from adjusting down a bit too low to get a nice squish. I have also off centered the print job to rule out any specific "worn" area or my PEI as well. Did you happen to load my profile and see anything set wrong? I was making a litho profile the other day and may have made a setting that is causing this...at a loss this moment.