See my two pics of PLA prints. The layers where the prints change I get extrusion issues. Maybe it's because it's the layer that goes from an infill to solid, or it's when there's a change in the amount of material for a layer. I'm not sure which settings apply.
It had happened on a previous print, but much worse, for the same type of layer changes. I had lowered the retraction settings a lot, which helped some, but not completely. Now they are as follows:
Multiplier 1.10, Width .40mm
Retr. Distance: .5mm, Speed: 50mm/s
No extra restart, no vertical lift, no coasting, no wiping,
Only retract when crossing spaces
No force retraction between layers,
minimum travel 10mm
Temp of Extruder: 230, bed 55, fan speed 60%
Using my Prusa i3 MK2S, white Shaxon PLA 1.75mm(from Frys)
Let me know if there are any other settings you'd like to know. As always, thanks in advance.