I posted this on the General Discussion page but, after testing in Slic3r, I believe it's a Simplify3d Print Preview BUG so, I'm posting a link to my post on the Discussion page
viewtopic.php?f=8&t=11449
It looks and prints correctly in Slic3r.
It prints correctly in Simplify, too.
But, the Print Preview in Simplify is NOT correct.