You can Manipulate the 3D view 2 ways. left click rotates your view around a point and right click PANS your view left right up down screen relative. of course the scroll wheel zooms in and out.
its extremely difficult to see anything close up in minute detail in Simplify 3D because unwanted PAN motion is mixed into desired view rotation motion.
IE as I try to rotate my viewpoint to see a tiny detail simplify 3D MOVES the mode view in PAN (vertically and always UP)
this makes it nearly impossible to lock in a good view of a really fine tiny detail because every time you try to adjust your view the pan motion MOVES the model away from the desired spot by moving up screen relative.
you can reproduce this easily. zoom in TIGHT on a model. use right click to get it where you want it now try left clicking to adjust viewing angle.
to exaggerate this effect make small circles while holding left click. the model will progressively move up screen relative constantly while you are moving with left click held. here is a video