I'm using 2.2.1 but I've seen this behavior since I started with S3D about a year ago.
Essentially If you select a profile, then change the material the temperatures (and many other settings) don't seem to follow across. It would be nice if changing the material also changed settings for that material. I've made a quick video showing what I'm seeing:
As it is now I have to select the material and then make a fair amount of changes to the profile to make sure everything is setup correctly. This seems to nullify the reason for having profiles in the first place.