I imagine there is going to be a lot of variance just based on what filament you are using, so I wouldn't be surprised if you still need to make a few adjustments even when using the stock profile. I would suggest starting here if you're having trouble with blobbing:
https://www.simplify3d.com/support/prin ... s-and-zits
After you work through those suggestions, if you're still having trouble, post some pictures of your prints so that others can help more