What do most of you have your multiplier set at? Ive had my extruder calibrated before i got S3D and Cura used to print fine, the only way i seem to not get blobs or pimples is when i use like a .8 extrusion multiplier, from other videos and things it seems really low and im worried about weak prints as well as im not getting a solid touching infill anymore.
I probably wouldn't try to tune your extrusion multiplier based on the blobs and zits you are seeing. Those are most likely due to retraction settings, not the extrusion multiplier.