Printer is a CR-10S. I have it modified with latest TH3D firmware, and an EZABL auto-bed leveling configuration (which is working very well). I'm printing with black Hatchbox PLA. Print temps are 200/70/C. Printer is in an enclosure, with typical ambient temps around 30/C. These settings typically work very well for me (though I do have trouble with stringing).
Basic print settings are 0.4mm nozzle, 1.20 ex mul, auto width, 5.00mm retract dist, 45mm/s retract, 50mm/s print speed, 10% infill, 0.2mm layer, 3 top, 3 bot, 1 shell, 50% overlap.
Since installing the EZABL and bed-leveling firmware, I've had much better success in not printing parts for the trash.