I too would like to use Simplify 3D with the MethodX. After they replaced my printer twice, I am still getting poor results when printing with support material. I sent them two files with which I've had problems, and they couldn't print them either. Their toolpath team is working on the problem. I don't consider what I am printing to be particularly demanding since I can print them on a FlashForge Creator Pro, an Ender Pro, and either my Form2 or Form3 Formlabs printer.
The printer itself is capable of doing excellent printing, but I have to mess with orientation, and even modifications to the models to get even satisfactory results. I replaced a five year old StrataSys uPrint that required extensive repairs with the MethodX expecting to get the same flawless ability to print with the SR30 support material, so I am hoping their team can get the software straightened out. If you folks were to make it possible to use Simplify3D, I'd be very interested in trying it out.