I really like Simplify3D, but it is MUCH more time consuming to configure a complex/multimaterial print than slic3r.
I've resorted to making a "profile" and exporting it in it's entirety (I think this is as intended).
For example, I've made a preset based on my slic3r profiles, and called it "T0 [30SP 0.2L 0.2F] [205-80 fan 1.75D PLA] [pbsm .4n E90]".
The first part describes the preset for the first extruder, and has the distinguishing features of a speed of 30 mm/s, 200um layers, and 20% infill.
The second shows it uses PLA at 205C for the extruder, 0 for the bed (not heated) and uses a software controlled fan and 1.75mm filament.
The third shows it's configured for my printrbot simple metal (startup Gcode and XYZE calibration values, etc) with a 0.4 mm nozzle and an extrusion calibration of 90 usteps/mm.
With slic3r I have like 40 profiles for printing and 20 each for the filament/printer sections,
To do this in simplify3d would be literally impossible, in a practical sense, of course. (16000 profiles?)
I would LOVE to see separate sections for each of these presets.
Currently, the only reason I use simplify3d is to accurately assign extruders to different parts of a multimaterial file.
Slicer doesn't do this quite right, and I'm getting into some pretty complicated configurations.
On a separate note, for dual extrusion, I have resorted to post processing with a find and replace tool (https://findandreplace.codeplex.com/) to change the extrusion calibration and turn on respective fans.
For my printing (biomedical research) I happen to be switching between a paste extruder and traditional plastic extruder, so the extrusion calibrations are vastly different (250 vs 45000 microsteps per mm)
Also, I have not seen a more elegant way to individually turn on a second fan since there is no support for this in the hardware (marlin, repetier) OR software (slic3r, cura, simpliofy).
Repetier has a nice (firmware) feature to run commands after selecting or deselecting an extruder, but what I'm really looking for here is to select a fan as the controlled fan (change which pin is controlled when using M106)
any thoughts?