I did a search for settings that need to change when changing nozzle sizes but I did not see much in this forum (which I find rather odd).
I just went from 0.4 to 0.6 I set the nozzle size in Simplify3D of course. And changed the Extrusion width to auto. And set the layer height to .15 ... increased the temp 10 deg and reduced the speed to 2500 mm/min (down from 3000).
Are there any other settings I should hit right away prior to doing a benchy?