It looks like this might be happening due to some over extrusion and/or curling. So when the nozzle goes to deposit the next layer it doesn't quite clear some of the previous layer and this can cause layer shifting like you see here.
The best way to fix this is to eliminate the over extrusion and curling. Some first steps to take would be to make sure you are printing at the lowest reasonable temperature for your material and to slow down your print speed to ensure each layer has time to cool before the next is deposited.
We have so more great tips in our Print Quality Guide so I have included a link to that below. Specifically the Overheating, Curling and Layer Shifting sections.
https://www.simplify3d.com/support/prin ... eshooting/