This is 100% a SOPHOS issue and not S3D! I was fighting the exact same issues for weeks!
If you can`t manage the IT department, you might just check the setting "properties" in sophos!
You can select a box there to dissable sophos for 4 hours + deselect all functions.
This will fix the issues for at least 4 hours .
Attention: All your settings/changes in settings won´t be stored/saved in the profile or taken into the gcode when Sophos is active!