In my own printing, I use several V5 settings almost constantly:
- Layer tab > "restrict start points to preferred regions" (this enables automated seam hiding)
- Infill tab > Dense Internal Infill (this adjust the density of the infill near the roof of the part, saving a lot of material usage)
- Infill tab > Solid Infill Threshold Area (this setting determines when small islands will be automatically reinforced with solid fill, which has definitely made small delicate prints stronger in my experience)
- Support tab > Support infill pattern (I've seen the grid pattern help a LOT with some of my taller prints that were previously too flimsy)
There are also a few settings only added in Version 5.1 that have helped a lot of parts with large flat top surfaces:
- Infill tab > Iron Top Layers (this enables ironing, which helps for parts with lots of flat surfaces)
- Advanced tab > enable "Only vertical lift on top layers" and go to Extruder tab > set Retract Vertical Lift to 0.5mm (changing both of these settings like you mentions enables Z lift only on the top layers, which also helps for parts with large top surfaces)
Those are may favorites, but interested to hear what other users like!