Okay. maybe not every single setting.

But at least the major ones. The nozzle size of course. Then the extrusion multiplier most likely and the width. Retraction almost certainly as well as retraction speed. Layer height temperature possibly. Cooling possibly. Print speed too. Bridging. Those are the main ones I had to change when I switched to the .8 mm from the .4 mm on the Craftbot Plus.
All of it really depends on what you are looking to achieve with the larger nozzle as mentioned.